With a single autotimer you can have one, two , three .... multiple TV channels of your choice to search. You can select all days of the week to search or you could restrict it to, say only Mondays and Wednesdays.
I tend not to restrict the time of day so the autotimer will search through all 24hrs per day. In nearly a decade of using OpenVix the number of recording that have been missed can be counted on one hand.
The only time I've set more than one Autotimer for a program was for Dr Who. The BBC decided to alternate the title between "Dr Who" and "Doctor Who". "Dr Who" does not equal "Doctor Who" when searching the EPG. Having a partial match on just "Who" is too general as it would, for instance, also pick up "Who do you think you are?", "Who wants to be a millionaire"? etc. etc.